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KMID : 1161920170140010004
Journal of Medicine and Life Science
2017 Volume.14 No. 1 p.4 ~ p.7
Eutypella species Isolated from a BronchoAlveolar Lavage in a Patient with Small Cell Lung Cancer
Yeo Seung-Joo

Kim Young-Ree
Kim Bong-Chan
Kang Sung-Ha
Abstract
The Eutypella is a genus of fungi in the family Diatrypaceae, and well-known plant pathogens, is capable of infecting many species of maple trees. We introduce here a case of Eutypella species isolated from a bronchoalveolar lavage in an immunocompromised patient with small cell lung cancer initially not suspected by SDA and LPCB stain and revealed by PCR and 18S rDNA sequencing. But, in this case, we couldn't judge whether this fungus was the pathogen for inflammation of lung and additional treatment was not needed for fungus isolation with no clinical problems. The human mycobiome includes 390 fungal species detected on the skin, in the vagina, in the oral cavity, and in the digestive tract that includes 335 species and 158 genera. Among these, 221 species are found only in the digestive tract, 88 only in the oral cavity, and 26 in both. These species belong to 126 genera of yeast and filamentous fungi, of the Ascomycota, Basidiomycota, and Zygomycota phyla. So, no matter how sensitive the diagnosis is, the results of molecular diagnosis method for fungal infection must be carefully considered with clinical conditions.
KEYWORD
Eutypella species, BronchoAlveolar Lavage, 18S rDNA sequencing
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